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KMID : 1123920040180051463
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Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 5 p.1463 ~ p.1470
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Effects of Paljinickmohwan on the Ovulation and Ovary in Rats
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Jung Woo-Suk
Kang Young-Keum
Choe Chang-Min
Kim Song-Baeg
Yoo Sim-Keun
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Abstract
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Paljinickmohwan(八珍益母丸) is used in female infertility. especially due to deficiency of qi and blood or Qihyulyanghe(氣血兩虛). An attempt was made to evaluate the influences of PJIMH on the serum concentrations of FSH, LH, and estradiol(E2), the histological changes of ovary and the immunohistochemical staining for AT2 receptor in ovary of rats. The results of the study were as follows : Blood FSH level significantly increased in experimental group as compared with control group. In blood LH level, experimental group as compared with control group showed no efficacy. Blood E2 level significantly increased in experimental group as compared with control group. In histological observations of ovary, ovulation increased in experimental group as compared control group, which showed no efficacy. In observations of immunohistochemical staining for AT2 receptor in ovary, there is no difference between control group and experimental group. According to these results, it can be concluded that PJIMH influences ovary to increase the ovulation of rats.
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KEYWORD
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Paljinickmohwan(八珍益母丸), Blood FSH level
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